Nociceptor α7nAChR activation blunts neuronal HMGB1 release and attenuates inflammation and nociceptive behavior.

Mol Med · 2025 · PMC12581301 · PMID 41184776

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highly significantno p-value reported

Quantitative analyses confirmed a highly significant reduction in nuclear-to-cytoplasm HMGB1 translocation following GTS-21 treatment (Fig. 8 D-E).

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