N-Lactoyl amino acids: insights from metabolite genome-wide association studies and phenome-wide association analysis.

Hum Mol Genet · 2025 · PMC12581823 · PMID 41015949

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hedged sentence

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

marginal significanceP -value = 0.053so close (0.05 < p ≤ 0.1)

The results revealed two pathways potentially associated with Lac-Tyr, which reached marginal significance: the biosynthesis from tryptophan to nicotinamide adenine dinucleotide (NAD + ) via quinolinate (adjusted P -value = 0.053), also known as Kynurenine pathway, and Mucin type O-glycan biosynthesis (adjusted P -value = 0.063).

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