Decreased Aryl Hydrocarbon Receptor Gene Expression and Polymorphic Variants Association with Increase COPD Risk.

Of note, the mild subgroup showed the lowest expression level of the AHR gene among four subgroups [6.92 ± 5.57 (mean ± SEM)]; however, in moderate, severe and very severe subgroups, the expression level of AHR gene decreased with increasing disease severity, while a decreasing trend in expression was observed from moderate to very severe subgroups ( Figure 6 and Table 8 ).

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