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Systematic study and 30-year projections of global and multi-regional burden of multiple sclerosis, 1990-2021.

Medicine (Baltimore) · 2025 · PMC12582701 · PMID 41261671

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an increasing trendno p-value reported
As shown in Figure 3 A, for the prevalence of MS, it showed an increasing trend in high SDI, medium SDI, medium to low SDI, and low SDI countries, and a stable trend in the world and high to medium SDI countries.

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a decreasing trendno p-value reported
As shown in Figure S8, Supplemental Digital Content, https://links.lww.com/MD/Q294 , the study on the deaths of MS showed that, on the whole, with the increase of SDI, the prevalence of MS showed a decreasing trend in Albania, Norway, Denmark, and other countries, while the United Kingdom showed an increasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.