A molecular convergence in the triad of parkinson's disease, depressive disorder and gut health is revealed by the inflammation-miRNA axis.

Furthermore, while a specific serotonergic pathway was not a top hit, key genes involved in 5-HT signaling, including the HTR2A and HTR2C , were integral components of other highly significant pathways, including PI3K-Akt signaling (KEGG: hsa04151, FDR < 10 − 5 ), indicating a broader dysregulation of monoaminergic neurotransmission (Fig. 1 M and O).

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