Optimizing early-phase immunotherapy trials: the role of biomarker enrichment strategies.

Front Immunol · 2025 · PMC12586187 · PMID 41200168

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may be significantno p-value reported

Therefore, the choice of detection method in early-phase trials may be significant, as it can influence the characterization of the enriched patient population and the subsequent interpretation of efficacy signals ( 63 ).

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