Potential Loss of Imprinting of Tumor Suppressor Gene RB1 in Triple Negative Breast Cancer.

To identify CpG85 differential methylation sites more accurately with LOI indicative significance in TNBC, 15 women with TNBC and 6 healthy women were included in the next study and cfDNA was isolated from their blood samples.

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With respect to hormone receptor-positive metastatic breast cancer, the use of cyclin-dependent kinase inhibitors (CDKi) has achieved major success and has become an increasing trend in clinical therapy.

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