Comparative Evaluation of Biocompatibility Data from the Subcutaneous and the Calvaria Implantation Model of a Novel Bone Substitute Block.

Differences were considered statistically significant at p ≤0.05 (* p ≤0.05), highly significant at p ≤0.01 (** p ≤0.01), and very highly significant at p ≤0.001 (*** p ≤0.001).

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Notably, moderate plasma cell infiltration was observed solely in the subcutaneous implantation beds of the biphasic bone substitute, with a decreasing trend over time.

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