Mutant p53 variants differentially impact replication initiation and activate cGAS-STING to affect immune checkpoint inhibition.

Commun Biol · 2025 · PMC12589595 · PMID 41193733

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highly significantno p-value reported

GSEA analysis reveals a highly significant enrichment of the interferon-alpha response gene set in the responder group, irrespective of the cancer types or the immune checkpoint inhibitors used (Fig. 10H and Fig.

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