The trend test for this graded association was highly significant ( P for trend < 0.001), demonstrating that the accumulation of multiple unfavorable SDoH substantially elevates hypertension risk in a dose-dependent manner. 3.5 Mediation analyses Given that adverse SDoH are associated with an increased risk of depression, we conducted a mediation analysis to examine whether depression partially mediated the relationship between adverse SDoH and hypertension.
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Association of social determinants of health and their cumulative inequities with risk of hypertension: a population-based study.
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