Should a repeat cervical cerclage be inserted when the primary cerclage fails, to prevent pregnancy loss and preterm birth? A systematic review and meta-analysis.

Although this was a highly significant odds ratio (p 0.0006), the poor quality evidence that this is based upon and the non-significant difference between the subgroups means conclusions are limited.

also in 47,871 other papers

Given the retrospective nature of the studies, selection bias is likely to be significant, whereby patients with clinically more severe failure (e.g., greater dilatation of the cervix at the point of diagnosis of failure, or greatest risk according to their previous history) may have been selected to have a repeat cervical cerclage over expectant management.

also in 492 other papers