Paternal valproate use and impact of shared genetic susceptibility on child neurodevelopment.

Associations between ASM exposure, epilepsy PRS, and child neurodevelopmental outcomes We investigated the differences in central tendency and distribution between the valproate exposed group and comparison groups and found a borderline significant difference between the valproate and lamotrigine/levetiracetam groups for motor difficulties at three years (difference in location of −0.74 [CI: −1.48– (−4.3*10 −6 )]; p ≈ 0.03; Figure S2).

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