Effectiveness and safety of low-dose intraoperative tranexamic acid in cardiac surgery: a retrospective before-and-after study.

In the IPTW-adjusted interrupted time series analysis, the reduction in the proportion of patients with ML exceeding 15% after intraoperative TXA implementation was not statistically significant but showed a decreasing trend ( β 2 = −1.47; 95% CI, −3.03 to 0.10; P = 0.066; Table 3 ).

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