Perivascular spaces, diffusion MRI markers and cognitive decline in cerebral small vessel disease.

Specifically, in individuals with sporadic SVD, it was linked to 0.10-SD better performance in processing speed at follow-ups, which showed a statistical trend when adjusted for age, sex, education, VRF score and SVD markers (Cohort 1: standardized β = 0.10, FDR-corrected p = 0.05; Table 2 ).

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