an increasing trendp < 0.001
On the other hand, the proportion from alveolar lavage fluid demonstrated an increasing trend, with rates of 1.4%, 2.4%, and 2.6% over the same period ( χ 2 = 35.71, p < 0.001) (Table 1 ). 3.4 Changes in Drug Resistance Rate of H. influenzae 3.4.1 β‐Lactamase Detection According to β‐lactamase test results from 2017 to 2023, the detection rate of β‐lactamase in H. influenzae increased consistently each year, with rates of 63%, 72.1%, 76.6%, 77.1%, 84.1%, 85%, and 88% ( χ 2 = 768.8, p < 0.001).