Cognitive reserve predicts baseline tau burden in the U.S. POINTER trial imaging cohort.

Alzheimers Dement · 2025 · PMC12598403 · PMID 41208717

Europe PMC DOI

hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

marginally significantp = 0.09so close (0.05 < p ≤ 0.1)

35 reported a marginally significant ( p = 0.09) increase in rate of tau accumulation associated with a 4 year decrease in CR‐EA in a cognitively impaired sample, but not a cognitively normal sample from the Mayo Clinic cohort.

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