With the percent treated in the no/unknown treatment group set between 2.5% and 30%, and the estimated HR plotted against the true HR on the absolute scale, the estimated HR may not seem to deviate too much from the true HR; however, the difference on the percent scale may be significant.
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Compliance With Recommendations of the Surveillance, Epidemiology, and End Results (SEER) Treatment Data Use Agreement: A Review of Published Studies.
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