Barely Significant
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Surfactant proteins A and D nucleotide variants: association with retinal vascular disease.

Pediatr Res · 2026 · PMC12600029 · PMID 41102472

2
hedged sentences
0.0520
closest p · 1.0× alpha
0.0520
boldest claim

The sentences

only marginally significantp = 0.052so close (0.05 < p ≤ 0.1)
The SNP rs17886395, noted as significantly associated with ROP but only under the Dominant model ( p = 0.026) in the complete cohort, is not only marginally significant ( p = 0.052) under this model, but is less significant ( p = 0.093) under the Additive model.

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However, when analyzed including covariates GA and duration of oxygen treatment in the analyses, both Additive (p = 0.068) and Dominant (p = 0.059), while not reaching significance, were perhaps marginally significant, as was perhaps alluded to by the shift of all the SFTPA2 SNPs towards marginal significance with the inclusion of these covariates noted earlier.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.