Barely Significant
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Hippocampal SGK1 promotes vulnerability to depression: the role of early life adversity, stress, and genetic risk.

Mol Psychiatry · 2025 · PMC12602343 · PMID 41034507

Europe PMCDOI
1
hedged sentence
0.0700
closest p · 1.4× alpha
0.0700
boldest claim

The sentences

marginally significantp = 0.07so close (0.05 < p ≤ 0.1)
When we stratified the data by sex as a biological variable, we found that the association between hippocampal SGK1 ePRS and depression diagnosis was marginally significant for boys (p = 0.07), and significant for girls (*p = 0.01); while the association between SGK1 ePRS and depressive symptoms was only significant for boys (*p = 0.02; Supplementary Table 3 ).

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