A critical role of FAK signaling in Rac1-driven melanoma cell resistance to MAPK pathway inhibition.

Oncogene · 2025 · PMC12602353 · PMID 41109929

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highly significantno p-value reported

This apparent contrast might be explained in part by the pleiotropy of Rac1 P29S-driven resistance mechanisms, in which several pathways make partial contributions to a collectively highly significant BRAFi-resistant phenotype.

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