Advanced glycated end-products modified transferrin mediates oxidative stress and ferroptosis in podocytes via advanced glycation end-product receptor in vitro.

Meanwhile, the results of the study showed that there was no significant difference in intracellular Fe2 + levels between NC, 5.6mMGlu-AGE-Tf, and 33.3mMGlu-AGE-Tf groups, the intracellular Fe 2+ levels showed a decreasing trend in 33.3mMGlu-AGE-Tf + DFO group compared to 33.3mMGlu-AGE-Tf group, but no significant difference was observed; and there was no significant trend of change between 33.3mMGlu-AGE-Tf and 33.3mMGlu-AGE-Tf + Fer-1 and 33.3mMGlu-AGE-Tf + RAP groups (Figure S2 ).

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