5 Average sperm counts have drastically decreased from 113 million/mL in 1940 to 66 million/mL in the 1990s, according to recent research, which is a worrying trend, 6 and decreased by 51.6 % from 1973 to 2018. 7 Male infertility can result from a range of factors including acquired urogenital abnormalities like blocked vas deferens, epididymitis, congenital issues e.g., undescended testes, ejaculatory duct cysts, endocrine disorders, environmental toxins like pesticides, smoking, genetic factors such as CFTR mutations, Klinefelter syndrome, and idiopathic causes.
← all excerpts
MicroRNA alterations in sperm of infertile men: Insights into oligozoospermia, asthenozoospermia, and teratozoospermia.
2
—
—
The sentences
In the asthenozoospermic group, miRNA-139 demonstrated even stronger diagnostic value, attaining a highly significant p-value of less than 0.0001 and an AUC of 0.8 ( Fig. 6 b), indicating its strong reliability in identifying asthenozoospermia cases.