Host cell state: an overlooked factor impacting the production of influenza A deletion-containing viral genomes and non-infectious particles.

However, at the genomic level, both strains showed an increasing trend of DelVG production with higher concentrations of alpelisib, with A/California/07/2009(H1N1pdm) infections pre-treated with 20 μM of alpelisib increasing polymerase complex segment DelVGs from 3.11%–4.40% (controls) to 24.67%–40.48%.

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