Global trends and inequalities in the burden of drug use disorders: a comprehensive analysis from 1990 to 2021 with future projections.

Front Public Health · 2025 · PMC12611819 · PMID 41246093

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a decreasing trendno p-value reported

In terms of prevalence, amphetamine use disorders (AAPC, −1.5), cannabis use disorders (AAPC, −0.2), cocaine use disorders (AAPC, −0.2), DUDs (AAPC, −0.2), and other drug use disorders (AAPC, −0.1) exhibited a decreasing trend, while opioid use disorders (AAPC, 0.8) showed the faster growth ( Figure 3C ).

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an increasing trendno p-value reported

The analysis revealed an increasing trend in DALYs for cocaine use disorders (AAPC, 0.8), DUDs (AAPC, 0.4), and opioid use disorders (AAPC, 0.9) ( Figure 3A ).

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