highly significantp<0.0001
Pro; OR: 1.12, 95% CI: 0.90-1.75), a recent observational cohort study showed a highly significant association between the R72 variant (G allele) and PCa risk (OR: 7.937; 95% CI: 5.37-11.0, p<0.0001) in a Caucasian population, but no statistically significant enrichment of the R72 variant in patients with higher Gleason score disease (≥8) [ 29 , 30 ].