NGF/ERK signaling-mediated epigenetic regulation of neuropathic pain in the cerebrospinal fluid-contacting nucleus.

Front Neurol · 2025 · PMC12614463 · PMID 41245866

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The rats treated with the NGF antibody showed a highly significant alleviation of neuropathic pain (NP) symptoms, as evidenced by increased MWT and TWL, indicating a significant reduction in mechanical allodynia (MA) and thermal hyperalgesia (TH), respectively ( Figure 3 ). 3.4.

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