Unveiling of phosphodiesterase-5 hot residues binding to xanthine derivatives for erectile dysfunction therapy: A computational drug repurposing approach.

PLoS One · 2025 · PMC12614580 · PMID 41231821

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hedged sentence

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closest p

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boldest claim

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highly significantno p-value reported

Asn662 was highly significant in stabilizing the linagliptin ligand, showing a hydrogen bond occupancy of 42% throughout the simulation.

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