Student's t -test or one-way analysis of variance (ANOVA) was applied to analyze data, with P < 0.05 indicating significant differences and P < 0.01 denoting highly significant differences. 3 Results and discussion 3.1 Characterization of drug loaded cRGD-GO To enhance the affinity of the prepared MN for tumor cells, we modified cRGD on GO to exhibit specific binding properties to the tumor cell surface receptor α v β 3 .
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Tumor cells targetable graphene oxide doped microneedle for synergistic photothermal-chemotherapy treatment of melanoma.
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