Barely Significant
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Single-residue engineering of lambda (λ) antibody light chains reduces conformational flexibility and enhances thermal stability.

Comput Struct Biotechnol J · 2025 · PMC12617621 · PMID 41245890

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0.0006
closest p · 0.0× alpha
0.0006
boldest claim

The sentences

highly significantP = 0.0006actually significant
3.5 Aggregate statistics across simulations In our simulations, we calculated the SD of elbow angles ( Supplementary Table S5 ) and defined flexibility as SD > 10°, because at the 10° threshold the mutant showed a highly significant shift (two-sided Fisher’s exact test, P = 0.0006; Supplementary Table S6 ).

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