Diagnostic oriented discrimination of different Shiga toxins via PCA-assisted SERS-based plasmonic metasurface.

ANOVA revealed highly significant statistical discrimination among the three toxins for both PC1 and PC2, with exceptionally low p-values ( Supplementary Material ).

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Interestingly, the analysis confirms that the distinctions between Stx2a and Stx1a, originating from two different genes and thus having different primary sequence, are more likely to be significant.

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