Current Insights and Future Perspectives for the Use of Serological Biomarkers in Polymyalgia Rheumatica.

25 Owens et al, also demonstrated the correlation of PLR with disease activity (defined by the mean PMR-activity score (PMR-AS)) during follow-up (OR 15.6; 95% CI 2.7–28.2), and there was also a trend towards significance for mean NLR and mean PMR-AS (OR 10.1, 95% CI 0.9–21.3). 53 A routinely available, acute phase soluble plasma protein, fibrinogen, has also been studied, and compared to both CRP and ESR, for its potential role in assessing disease activity in PMR, where it was found to be more specific than either

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53 Notably, a trend toward significance for baseline PLR (OR 5.02; 0.49–71.54) in predicting GC-resistance was also observed. 53 There are conflicting results in the literature regarding the utility of ESR and CRP in disease prognostication and predicting glucocorticoid remission in PMR.

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