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New approach to optimize therapy in type 2 diabetes mellitus: the importance of subclassification.

Front Endocrinol (Lausanne) · 2025 · PMC12620229 · PMID 41255523

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markedly significantno p-value reported
CIRDD The more aggressive phenotype of this group characterized by difficult-to-control hyperglycemia, a product of the combination of insulin deficiency and resistance, together with overweight, dyslipidemia and markedly significant risks of cardiovascular, renal and retinopathy disease, makes it necessary to intensify treatment compared to SIDD and SIRD.

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