Distinct Epitopes Are Associated With Clinical Phenotypes in Autoimmune Nodopathies With Anti-Contactin1 Autoantibodies.

Comparison of outcomes tended to differ but failed to reach significance within the limited cohort size: Two of the 3 patients with binding to the FnIII domain showed a chronic course of disease, whereas in the patients with an Ig epitope, autoantibodies detected by routine diagnostic testing only persisted in a single patient (analyzed 7 months after onset) and in 8 patients, no positive signals were detectable during the course of disease.

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