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Metformin in non-diabetic patients with autosomal dominant polycystic kidney disease: a systematic review and meta-analysis of randomized controlled trials.

BMC Nephrol · 2025 · PMC12625526 · PMID 41254555

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a possible trendno p-value reported
Nevertheless, the numerically less pronounced decline in the metformin group may suggest a possible trend toward kidney protection, though this finding should be interpreted with caution.

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