Comparative effectiveness of darbepoetin vs other agents in chronic kidney disease-related anemia: a systematic review and network meta-analysis.

In additional analyses, Daprodustat significantly improved hemoglobin compared to darbepoetin (mean difference +0.15 g/dL, 95% CrI: 0.03 to 0.29), whereas Roxadustat showed a nonsignificant trend toward improvement (+0.12 g/dL, 95% CrI: −0.05 to 0.27) as shown in Fig. 2 (A-E) Transferrin saturation Changes in transferrin saturation were modest across treatment arms.

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