Multi-omics analysis reveals the mechanism of <i>Lactobacillus plantarum</i> in alleviating metabolic disorders in type 2 diabetic mice through the gut-liver axis.

mSystems · 2025 · PMC12625740 · PMID 41165343

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highly significantno p-value reported

For instance, the increase in secondary bile acids (such as DCA and LCA derivatives) we detected is highly significant, as these specific metabolites are well-characterized as potent natural agonists for TGR5 ( 47 , 48 ).

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