Global Burden of Inflammatory Bowel Disease Among Women of Reproductive Age From 1990 to 2021 and Future Projections to 2050: A Comprehensive Analysis Using Eight Machine Learning Algorithms.

Additionally, while the ASDR and ASMR in the Middle SDI region have shown a decreasing trend, the increases in ASIR and ASPR have been the most pronounced, suggesting that IBD burden continues to rise in this region and further interventions are necessary ( Figures 1 and 2 , Tables 1 and S1 – 3 ).

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Over the past 32 years, the Low SDI region has experienced the highest growth rates in incidence, prevalence, DALYs, and mortality, and is the only region where ASIR, ASPR, ASDR, and ASMR all show an increasing trend.

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