In contrast, other studies have observed an increasing trend in the voriconazole trough concentrations during co-administration with nirmatrelvir/ritonavir, a finding inconsistent with the prescribing information of nirmatrelvir/ritonavir ( Shi et al., 2025 ; López-Hernández et al., 2025 ).
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A case report of drug-drug interaction between voriconazole and simnotrelvir/ritonavir.
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