The cell line with TIMP1 expression from the inactive X (cell line 2 – HSC593) showed a small trend towards having a lower percentage of cells that replicated asynchronously than the GM07059 cell line which does not have TIMP1 expression from the inactive X (25% vs 29%); however this difference was not significant (P = 0.17).
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Epigenetic predisposition to expression of TIMP1 from the human inactive X chromosome.
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