PIK3R3 regulates differentiation and senescence of periodontal ligament stem cells and mitigates age-related alveolar bone loss by modulating FOXO1 expression.

J Adv Res · 2025 · PMC12627332 · PMID 39862908

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PI3K is a highly significant kinase in cells, garnering considerable attention over an extended period [12] , [13] , [14] .

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