40 , 41 From the perspective of EWSs, including variance and autocorrelation, an increasing trend in variance and a decreasing trend in autocorrelation are observed as precursors to the bifurcation, aligning with theoretical analyses of traditional detection methods prior to Pd bifurcations in dynamical systems. 42 However, these indicators exhibit poor performance on non-bifurcation data, as fluctuating trends in both autocorrelation and variance can still occur, potentially leading to false positives.
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FatePredictor: Cell fate decision-making prediction with an ensemble deep learning model.
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