Barely Significant
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Effectiveness of treatment initiation for secondary fracture prevention in the older population: Japanese Bone-fracture Osteoporosis in Late-stage population Database study (J-BOLD) - emulation of a randomized target trial.

Osteoporos Int · 2025 · PMC12628409 · PMID 40903594

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a decreasing trendno p-value reported
Although a decreasing trend in the risk of vertebral, radial, and humeral fractures was noted, statistical significance was not consistently observed across all subgroups stratified by follow-up duration and sex.

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