Effects of removable clear dental aligners on the composition of the oral microbiome.

For instance, in saliva, we detected a decreasing trend in the species Corynebacterium matruchotii , which was consistent after 3 and 6 months of treatment.

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Despite the fact that no significant results were found in our study, a small trend in the decrease in richness over time was visually apparent, although the limited sample size may have resulted in a lack of statistical power.

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Conversely, Actinomyces viscosus and Actinomyces gerencseriae were found to have an increasing trend in the salivary microbiome at 3 and 6 months, respectively, and this genus is associated with caries formation [ 39 ], [ 9 ].

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