Epigenome-wide profiling of trisomy 18 specific DNA methylation signatures in first-trimester chorionic villi.

Clin Epigenetics · 2025 · PMC12628925 · PMID 41257854

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highly significantno p-value reported

PPI enrichment was highly significant (FDR < 2.9 × 10 −13 ). 65 genes associated with hypermethylated DMR (shown in red), 14 genes associated with hypomethylated DMR (blue), and one gene contained both hyper- and hypomethylated DMRs (green) were constructed the signal complex.

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