Global, regional, and national burden of early-onset and late-onset colorectal cancer attributable to high body-mass index from 1990 to 2021: a trend analysis and forecasts up to 2040 based on the global burden of disease study 2021.

Between 1990 and 2021, the global ASDR and ASMR of EOCRC attributable to HBMI exhibited an increasing trend in both males and females.

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For LOCRC, the overall burden in High SDI districts has shown a gradual decline, with subgroup analysis indicating a decreasing trend in both genders in High SDI districts and among females in High Middle SDI districts, while other SDI regions and genders continue to experience an increasing trend.

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