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Engineering Three-Dimensional Cellular Organization by Regulating Bound Water-Mediated Cell-Substrate Interactions for Disease Modeling.

ACS Omega · 2025 · PMC12631434 · PMID 41280840

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The results showed a tendency for increased gene expression of both IL-6 and IL-1β in the MASH model supplemented with FFAs. Furthermore, in the resmetirom-treated MASH model, a decreasing trend in the expression of these inflammatory cytokines was observed ( Figure d).

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