For the morphology-related proteins and transporter expression response to HI in ChP organoids, the annotation of the top leading-edge genes of the brush border of ChP gene set showed highly significant enrichment of three categories related to the organization of brush ChP, cells cytoskeleton and adhesion, and molecules transport systems (Fig. 4 A).
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Translational biomarkers of hypoxic brain injury uncovered in CSF secreting human choroid plexus organoids.
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