The cumulative excretion rates of peak concentration (C max ), area under the curve (AUC 0-t and AUC 0 − ∞ ), and exhaled gas in blood and exhaled gas do not follow a dose linear relationship due to individual differences; however, the observed average values demonstrate an increasing trend.
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Evaluation of the pharmacokinetics, pharmacodynamics, and liver ultrasound imaging characteristics of a novel perfluoropropane microbubble in Chinese volunteers.
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