JNK knockdown enhances CAR-T cell cytotoxicity through elevated NFATc1-dependent transcription in preclinical ovarian cancer models.

J Immunother Cancer · 2025 · PMC12636948 · PMID 41253493

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highly significantno p-value reported

This is highly significant since it can considerably enhance the anticancer performance of CAR-T cells by just incorporating the shJNK expression cassette into any CAR vectors in use.

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