The B169L protein of African swine fever virus functions as a viroporin that activates the calcium-mediated inflammasome.

PLoS Pathog · 2025 · PMC12638030 · PMID 41237200

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highly significantno p-value reported

In comparison with the pB169L group, the mutations at residues P29, I31, V52, K55, R56, and K57 exhibited highly significant inhibitory effects (with a fold change of > 2) ( Fig 5D ).

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